Vijay G. Sankaran, M.D., Ph.D.
Dana-Farber Cancer Institute
Harvard Medical School
Dr. Vijay Sankaran’s laboratory aims to understand how genetic variation alters human blood cell production or hematopoiesis in health and disease.
The Sankaran laboratory has identified over a dozen genes implicated in congenital forms of anemia and other blood disorders. In addition, the laboratory has identified key regulators of fetal and other hemoglobin subtypes in humans.
A major ongoing emphasis of the laboratory is to be able to use genomic technologies, including modern sequencing approaches and massively parallel assays, to more comprehensively define both common and rare genetic variation underlying alterations in blood production found in patients with blood disorders and in healthy individuals.
The laboratory also has a strong interest in using insight from human genetic studies to develop improved autologous stem cell-based therapies to treat numerous blood disorders and to identify approaches to induce fetal hemoglobin for therapy of the hemoglobin disorders.
Dr. Vijay G. Sankaran is Interim Chief, Division of Hematology/Oncology, Boston Children’s Hospital/Institute Physician; Lodish Family Chair, Boston Children's Hospital; Attending Physician, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, and Associate Professor of Pediatrics, Harvard Medical School. He received a B.A. and M.S. from the University of Pennsylvania in biochemistry, an M.Phil. from the University of Cambridge in biochemistry, and earned his M.D. and Ph.D. degrees from Harvard Medical School. He subsequently did a residency in pediatrics at Boston Children’s Hospital and Boston Medical Center, followed by a fellowship in pediatric hematology/oncology at Boston Children’s Hospital and the Dana-Farber Cancer Institute. Dr. Sankaran has received a number of awards for his work on using human genetics to better understand the process of blood cell production, including most recently the 2015 Young Investigator Award from the Society for Pediatric Research and the 2014 Cohen Memorial Lectureship from the Children’s Hospital of Philadelphia.
Division of Hematology/Oncology
Center for Life Sciences